Saw Palmetto Berry Extract

Botanicalmen's healthModerate dose evidence

Also known as: Serenoa repens, Sabal serrulata, saw palmetto oil extract, saw palmetto lipidosterolic extract

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A lipid-sterol extract of saw palmetto berries, standardized to fatty acids, that is the most widely used botanical in men's prostate and urinary-comfort products. It has been tested in dozens of randomized trials at 320 mg per day; a Cochrane review concluded that it did not outperform placebo on urinary symptom scores at standard or escalated doses, so confidence in its clinical effect is tempered even though it remains commercially dominant. The extract is oily and suits softgels.

Research summary

Fatty acids and phytosterols are proposed to inhibit 5-alpha-reductase and modulate androgen receptor activity in prostate tissue.

Dosage

Daily amounts, of extract.

Lowest studiedTypical rangeHighest studiedUpper limit
320 mg960 mg

320 mg per day of an 85 to 95% fatty-acid extract, as a single softgel or 160 mg twice daily with food. Trials in the Cochrane review used 320 mg per day, with one escalating to 960 mg without added benefit. Give at least 12 weeks before judging effect.

Standardization: 85–95% fatty acids and sterols

Source material: berry supercritical CO2 or hexane extract (oil)

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Oil-based; softgel is the standard format. Powdered berry (not extract) exists for capsules but is a different ingredient.

Formulation notes

Frequently combined with beta-sitosterol, pumpkin seed oil, zinc, or nettle root. Rancidity is a concern; request peroxide values.

Sources

  1. Serenoa repens for benign prostatic hyperplasia. (Tacklind 2012)PubMed
  2. Saw Palmetto — ExamineExamine

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