Vitamin C (Calcium Ascorbate)

Vitaminwater-solubleStrong dose evidence

Also known as: calcium L-ascorbate, calcium ascorbate dihydrate, buffered vitamin C, E302

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Calcium ascorbate is the calcium salt of vitamin C, commonly supplied as the dihydrate. It is a non-acidic, gentle-on-the-stomach vitamin C source that also contributes a small amount of calcium, so it is popular in buffered vitamin C tablets and in formulas where a sodium-free buffered form is wanted. Per gram it supplies roughly 820 mg of ascorbate and about 95 mg of calcium.

Research summary

Dissociates to ascorbate and calcium ions in the gut; the ascorbate is absorbed and functions identically to ascorbic acid.

Dosage

Daily amounts, elemental (82% of the compound is the element).

Lowest studiedTypical rangeHighest studiedUpper limit
90 mg250–1,000 mg2,000 mg2,000 mg

NIH ODS — UL is 2,000 mg/day of vitamin C for adults 19+; applied to ascorbate content

Doses are mg of ascorbic acid equivalent. Elemental fraction 0.82 is stoichiometric for the dihydrate: two ascorbate ions (2 x 175.1) divided by calcium ascorbate dihydrate MW 426.3 = 0.82; anhydrous material is closer to 0.90, so verify against the supplier CoA. 1,000 mg vitamin C needs about 1,220 mg of the dihydrate and brings roughly 115 mg calcium (9.4 percent of the salt). Same RDA and UL as ascorbic acid.

Standardization: ≥98% calcium L-ascorbate dihydrate

Source material: synthetic (ascorbic acid neutralized with calcium carbonate)

Forms of Vitamin C

FormTypical doseElement %FormatsPrice
Vitamin C (Calcium Ascorbate)250–1,000 mg82%Capsule, Powder, Tablet, Gummy, Liquidlow
Vitamin C (Ascorbic Acid)250–1,000 mgCapsule, Powder, Tablet, Gummy, Liquidlow
Vitamin C (Sodium Ascorbate)250–1,000 mg89%Capsule, Powder, Tablet, Gummy, Liquidlow
Vitamin C (Ascorbyl Palmitate)42%Softgel, Liquid, Capsulemid

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Neutral taste; works well in chewables and buffered tablets.

Formulation notes

Adds calcium; include it when totaling calcium in a formula. Sodium-free alternative to sodium ascorbate.

  • Has an upper limit

Sources

  1. Vitamin C — Health Professional Fact SheetNIH ODS
  2. Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. (Levine M, 1996)PubMed

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