Caffeine Anhydrous

Sports performancestimulantStrong dose evidence

Also known as: caffeine, synthetic caffeine

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Purified, dehydrated caffeine — the standard stimulant in pre-workouts, energy, and focus products. It reliably improves alertness, perceived effort, and endurance performance. Because the dose per serving is small, it fits easily into any format, but total caffeine per serving must be managed carefully.

Research summary

Adenosine receptor antagonist; increases catecholamine release and reduces perceived exertion.

Dosage

Daily amounts, of compound.

Lowest studiedTypical rangeHighest studiedUpper limit
50 mg100–200 mg400 mg

No formal UL. FDA cites 400 mg/day as generally not associated with negative effects in healthy adults; the app treats 400 mg per serving as an error and 200 mg as a warning.

3–6 mg/kg body weight is the performance dosing range in the literature; 100–200 mg per serving covers most consumers. Half-life is roughly 5 hours, so avoid in sleep-adjacent products. Tolerance builds with daily use.

Standardization: ≥98.5% caffeine

Source material: synthetic

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Bitter; powders need masking above ~150 mg per serving.

Formulation notes

Pair with L-theanine to reduce jitters. Count caffeine from guarana, green tea, yerba mate, and coffee fruit toward the total.

  • Stimulant
  • Contains caffeine
  • Not for pregnancy

Sources

  1. International society of sports nutrition position stand: caffeine and exercise performance (Guest 2021)PubMed
  2. Spilling the Beans: How Much Caffeine is Too Much?FDA

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