Creatine Monohydrate
Also known as: creatine, micronized creatine, Creapure
The most researched sports supplement in existence. Creatine monohydrate increases phosphocreatine stores in muscle, supporting short, high-intensity efforts, training volume, and lean mass gains. It also has a growing evidence base for cognitive and healthy-aging applications. Micronized grades mix better in powders.
Research summary
Raises intramuscular phosphocreatine, speeding ATP regeneration during high-intensity exercise.
Dosage
Daily amounts, of compound.
| Lowest studied | Typical range | Highest studied | Upper limit |
|---|---|---|---|
| 3 g | 3–5 g | 20 g | — |
3–5 g daily saturates muscle stores within about four weeks; an optional loading phase of 20 g/day (split into 4 doses) for 5–7 days saturates faster. Timing relative to training matters little. Doses are of the monohydrate compound (about 88% creatine by mass).
Source material: synthetic
Forms of Creatine
| Form | Typical dose | Element % | Formats | Price |
|---|---|---|---|---|
| Creatine Monohydrate | 3–5 g | — | Powder, Capsule, Tablet, Gummy | low |
| Creatine Hydrochloride | 1.5–3 g | — | Powder, Capsule, Tablet, Liquid, Gummy | mid |
Format suitability
- Capsule
- Powder
- Tablet
- Softgel
- Gummy
- Liquid
A 5 g dose is 7+ size-00 capsules — powder is the practical format. Degrades to creatinine in liquids; gummies are possible but stability must be validated with the manufacturer.
Formulation notes
Often combined with carbohydrates or protein; commonly stacked with beta-alanine and citrulline in pre-workouts.
Sources
Related ingredients
Essential Amino Acid (EAA) Blend
Sports performanceA free-form blend of all nine essential amino acids, typically leucine-weighted, that provides the complete substrate for muscle protein synthesis without the bulk of a full protein serving.
Typical: 6–15 g
HMB (Beta-Hydroxy Beta-Methylbutyrate)
Sports performanceA metabolite of leucine studied for reducing exercise-induced muscle protein breakdown and supporting strength and lean mass, particularly in untrained people, older adults, and during intense training blocks.
Typical: 3 g
L-Leucine
Amino acidThe branched-chain amino acid that most directly triggers muscle protein synthesis through mTOR signaling.
Typical: 2.5–5 g
Whey Protein Isolate
ProteinWhey filtered to 90% or more protein by weight, with most lactose and fat removed.
Typical: 20–30 g
Whey Protein Concentrate
ProteinWhey concentrated by ultrafiltration to 70–80% protein, retaining more lactose, fat, and native bioactive fractions than isolate.
Typical: 25–35 g