Best ingredients for memory
Learning, recall, and long-term cognitive support. These ingredients are studied for or commonly used for memory. Doses on each page come from NIH guidance and published research.
Creatine Monohydrate
Sports performanceThe most researched sports supplement in existence.
Typical: 3–5 g
Fish Oil (EPA/DHA Concentrate)
Fatty acidFish oil concentrate is a refined marine oil enriched in the long-chain omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Typical: 500–2,000 mg
Lion's Mane (Hericium erinaceus)
MushroomLion's mane is an edible tooth fungus whose fruiting body and mycelium contain hericenones and erinacines alongside beta-glucan polysaccharides.
Typical: 500–1,000 mg
Ginkgo Biloba Extract
NootropicA leaf extract from the ginkgo tree standardized to flavone glycosides and terpene lactones, long used in memory and circulation formulas.
Typical: 120–240 mg
Acetyl-L-Carnitine
Amino acidAn acetylated form of carnitine that crosses the blood-brain barrier more readily than carnitine itself and donates acetyl groups for acetylcholine synthesis.
Typical: 500–2,000 mg
Algal DHA (Algae Oil)
Fatty acidAlgal DHA is docosahexaenoic acid produced by fermenting marine microalgae such as Schizochytrium, the same organisms that fish obtain their DHA from.
Typical: 200–500 mg
Bacopa Monnieri Extract
NootropicAn extract of a creeping wetland herb from traditional Indian practice, standardized to bacosides, that is one of the better-studied botanical nootropics for memory.
Typical: 300–450 mg
Magnesium L-Threonate
MineralA magnesium salt of L-threonic acid, a vitamin C metabolite, developed at MIT as a form that raises brain magnesium in animal models.
Typical: 100–144 mg
Phosphatidylserine
NootropicPhosphatidylserine is a phospholipid concentrated in neuronal membranes where it supports receptor function, neurotransmitter release, and signaling.
Typical: 100–300 mg
Huperzine A
NootropicHuperzine A is an alkaloid from the club moss Huperzia serrata that reversibly inhibits acetylcholinesterase, raising acetylcholine levels in the brain.
Typical: 50–200 mcg
Choline Bitartrate
VitaminCholine bitartrate is the tartaric acid salt of choline and the most economical way to add this essential nutrient to a formula.
Typical: 250–550 mg
Alpha-GPC
NootropicAlpha-GPC is a water-soluble phospholipid metabolite that delivers choline across the blood-brain barrier more efficiently than choline salts, which is why it anchors many focus and memory formulas and pre-workout blends.
Typical: 300–600 mg
Curcumin Solid Lipid Particle (Longvida)
BotanicalA branded curcumin formulation in which curcumin is embedded in solid lipid particles to protect it from degradation in the gut and support delivery of free curcumin into circulation.
Typical: 400–800 mg
American Ginseng Extract
BotanicalThe root of a ginseng species native to North America, used in focus and calm-energy formulas.
Typical: 200–400 mg
Citicoline (CDP-Choline)
NootropicCiticoline is a naturally occurring nucleotide that splits in the gut into choline and cytidine (converted to uridine), giving the brain both a choline source for acetylcholine and phosphatidylcholine and a uridine source for membrane synthesis.
Typical: 250–500 mg
Lithium Orotate
OtherA salt of lithium with orotic acid sold at microgram-to-low-milligram lithium doses, hundreds of times below prescription lithium carbonate.
Typical: 1–5 mg
Gotu Kola Extract
BotanicalAn extract of a small creeping herb used across Asian traditional systems and now included in cognitive, skin, and circulation formulas.
Typical: 500–1,000 mg
PQQ (Pyrroloquinoline Quinone)
AntioxidantPyrroloquinoline quinone is a redox cofactor found in trace amounts in foods such as natto, kiwi, and green tea.
Typical: 10–20 mg
Sunflower Lecithin
Fatty acidSunflower lecithin is a mixture of phospholipids, chiefly phosphatidylcholine, phosphatidylinositol, and phosphatidylethanolamine, separated from sunflower oil during degumming.
Typical: 1,200–2,400 mg
Maitake (Grifola frondosa)
MushroomMaitake is a clustered, edible polypore whose proprietary beta-glucan extract, D-fraction, has been studied in small oncology and immunology trials, including a phase II study in myelodysplastic syndromes.
Typical: 500–2,000 mg
Pterostilbene
AntioxidantPterostilbene is a methylated analog of resveratrol found in blueberries and Pterocarpus wood.
Typical: 50–250 mg
Spermidine (Wheat Germ Extract)
OtherSpermidine is a naturally occurring polyamine found in wheat germ, aged cheese, soybeans, and mushrooms.
Typical: 1–6 mg
Luteolin
AntioxidantLuteolin is a flavone found in celery, parsley, peppers, and chamomile that is studied for mast-cell stabilization and neuro-inflammatory signaling.
Typical: 100 mg