Lactobacillus gasseri

Probioticlactic acid bacteriaModerate dose evidence

Also known as: L. gasseri, SBT2055, LG2055, CP2305, BNR17, Lactobacillus gasseri SBT2055

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Lactobacillus gasseri is a human-origin lactic acid bacterium found in the gut and vaginal microbiota. It gained attention through a 12-week randomized trial of fermented milk containing strain SBT2055 that measured abdominal fat and body weight in adults with obese tendencies, and it is now positioned in weight-management and metabolic formulas as well as women's health blends. Freeze-dried powders at 1–10 billion CFU per serving are widely available. Evidence is strain-specific and most of it comes from Japanese and Korean trials, so results with other strains should not be assumed.

Research summary

Studied for effects on dietary fat absorption, adipose tissue signaling, and vaginal pH.

Dosage

Daily amounts, of compound. CFU shown in billions.

Lowest studiedTypical rangeHighest studiedUpper limit
1 B CFU1–10 B CFU

Amounts are in billions of CFU (enter 5 for 5 billion). Raw-material weight assumes a 100 billion CFU/g concentrate (10 mg per billion CFU); manufacturers add a 20–50% CFU overage at fill so the label claim holds through shelf life, and the label should state whether CFU are guaranteed at manufacture or at expiry. The SBT2055 trial delivered the strain in 200 g of fermented milk daily, not a capsule, so capsule doses are extrapolated.

Standardization: Strain-designated freeze-dried culture; CFU per gram on CoA

Source material: freeze-dried culture

As supplied: Assumes 100 billion CFU/g concentrate (10 mg per billion CFU); adjust to supplier CoA.

Forms of Lactobacillus

FormTypical doseElement %FormatsPrice
Lactobacillus gasseri1–10 B CFUCapsule, Powdermid
Lactobacillus acidophilus1–10 B CFUCapsule, Powdermid
Lactobacillus reuteri (DSM 17938)0.1–1 B CFUCapsule, Powderhigh
Lactobacillus plantarum1–10 B CFUCapsule, Powdermid
Lactobacillus casei1–10 B CFUCapsule, Powdermid

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Heat- and moisture-sensitive vegetative cells; capsule or dry powder only.

Formulation notes

Separate from antibiotic dosing by at least two hours. Keep water activity low in the finished product.

Sources

  1. NIH ODS — Probiotics Fact Sheet for Health ProfessionalsNIH ODS
  2. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. (Kadooka 2010)PubMed

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