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Nettle Root

Botanicalmen's healthModerate dose evidence

Also known as: Urtica dioica root, stinging nettle root, Urticae radix

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Nettle root is the underground part of Urtica dioica, distinct from the leaf in both chemistry and use. Root preparations contain lignans, sterols, and polysaccharides and are used in men's health formulas, most often combined with saw palmetto or pygeum for prostate and urinary comfort. Several randomized trials have used dry root extracts in men with lower urinary tract symptoms. Products are typically supplied as a 4:1 to 10:1 extract or as milled root powder.

Research summary

Studied for interaction with sex-hormone binding globulin and for effects on prostate cell signaling.

Men's hormonesGeneral health

Dosage

Daily amounts, of extract.

Lowest studiedTypical rangeHighest studiedUpper limit
300 mg300–600 mg——

Usually divided into two doses with food. Trials used dry extracts over 6 to 12 months; onset is gradual.

Standardization: Root extract (commonly 4:1 to 10:1); no universal marker

Source material: root extract

Forms of Nettle

FormTypical doseElement %FormatsPrice
Nettle Root300–600 mg—Capsule, Powder, Tabletlow
Nettle Leaf300–600 mg—Capsule, Powder, Tabletlow

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Earthy taste; capsules preferred.

Formulation notes

Commonly combined with saw palmetto, pygeum, and pumpkin seed.

Sources

  1. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. (Safarinejad MR 2005)PubMed

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