Rutin
Also known as: rutoside, quercetin-3-rutinoside, vitamin P, Sophora japonica rutin
Rutin is the glycoside of quercetin bound to the sugar rutinose, usually extracted from Sophora japonica or buckwheat. It is a traditional ingredient in circulation and vein-support formulas and is commonly combined with vitamin C, hesperidin, and diosmin. In the gut, bacteria remove the sugar to release quercetin, so rutin acts partly as a slow-release quercetin source. It is inexpensive and stable, which makes it a common filler flavonoid in bioflavonoid complexes.
Research summary
Studied for antioxidant activity and for effects on capillary permeability after conversion to quercetin.
Dosage
Daily amounts, of compound.
| Lowest studied | Typical range | Highest studied | Upper limit |
|---|---|---|---|
| 250 mg | 250–500 mg | — | — |
Typically taken once or twice daily with meals. A human supplementation study used 500 mg per day; dose-response data are limited.
Standardization: ≥95% rutin
Source material: Sophora japonica bud extract
Format suitability
- Capsule
- Powder
- Tablet
- Softgel
- Gummy
- Liquid
Yellow-green powder with mild bitterness.
Formulation notes
Often paired with vitamin C in bioflavonoid blends.
Sources
Related ingredients
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Vitamin E (d-Alpha-Tocopheryl Succinate)
VitaminThe succinate ester of natural (RRR or d-) alpha-tocopherol, the one vitamin E form the body maintains in plasma and the form on which the RDA is based.
Typical: 67–268 mg
Trans-Resveratrol
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Typical: 150–500 mg
CoQ10 (Ubiquinol)
AntioxidantUbiquinol is the reduced, active antioxidant form of coenzyme Q10 and the form that predominates in blood.
Typical: 100–200 mg