Gotu Kola Extract
Also known as: Centella asiatica, brahmi (Centella), asiaticoside, Indian pennywort, TECA
An extract of a small creeping herb used across Asian traditional systems and now included in cognitive, skin, and circulation formulas. A two-month trial in healthy older adults using 250, 500, and 750 mg per day reported improvements in working memory and mood, most clearly at the highest dose, and a systematic review found supportive but limited evidence for cognitive and mood outcomes. It is typically standardized to triterpenes and is a common partner to bacopa in memory blends.
Research summary
Triterpenes such as asiaticoside and madecassoside are proposed to support cholinergic signaling, dendritic growth, and collagen synthesis, and to reduce oxidative stress.
Dosage
Daily amounts, of extract.
| Lowest studied | Typical range | Highest studied | Upper limit |
|---|---|---|---|
| 250 mg | 500–1,000 mg | — | — |
500 to 1,000 mg per day of extract, split with meals; the dose-ranging trial used 250 to 750 mg once daily for two months. Cognitive effects were assessed after four to eight weeks.
Standardization: 10% asiaticosides (or total triterpenes)
Source material: whole-herb extract
Format suitability
- Capsule
- Powder
- Tablet
- Softgel
- Gummy
- Liquid
Mild, slightly bitter, grassy flavor; workable in powders.
Formulation notes
Often combined with bacopa, ginkgo, or collagen. Rare reports of liver effects at high doses; keep to studied amounts.
- Not for pregnancy
Sources
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