Krill Oil

Fatty acidomega-3Moderate dose evidence

Also known as: Antarctic krill oil, Euphausia superba oil, phospholipid omega-3, krill omega-3

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Krill oil is extracted from Antarctic krill (Euphausia superba), a small crustacean. Unlike fish oil, a large share of its EPA and DHA is bound to phospholipids rather than triglycerides, and it naturally contains the carotenoid astaxanthin, which gives it a red color and some oxidative stability. Total EPA+DHA per gram is lower than in fish oil concentrates, so krill oil is dosed as milligrams of whole oil. It is commonly used in heart, joint, and general omega-3 products marketed on absorption and small softgel size.

Research summary

Supplies EPA and DHA in phospholipid form plus astaxanthin; the phospholipid carrier is proposed to aid incorporation of omega-3s into cell membranes.

Dosage

Daily amounts, of compound.

Lowest studiedTypical rangeHighest studiedUpper limit
500 mg500–2,000 mg

Dosed as mg of whole krill oil. Typical products supply 500-1,000 mg oil per softgel containing roughly 100-250 mg combined EPA+DHA, so a 2,000 mg dose still delivers less EPA+DHA than 1,000 mg of a 60% fish oil concentrate. Pooled trial data show lipid changes over at least two weeks of daily use. Highest dose across the pooled trials was not extracted from the abstract and is left null. Take with food.

Standardization: Declare phospholipid content (commonly about 40%), EPA and DHA mg, and astaxanthin content

Source material: whole Antarctic krill, solvent or enzymatic extraction

As supplied: EPA+DHA content varies by supplier (roughly 12-25% of oil mass); check the CoA

Forms of Omega-3

FormTypical doseElement %FormatsPrice
Krill Oil500–2,000 mgSoftgel, Liquidhigh
Fish Oil (EPA/DHA Concentrate)500–2,000 mgSoftgel, Liquidmid
Algal DHA (Algae Oil)200–500 mgSoftgel, Liquidhigh
Cod Liver Oil1,000–2,000 mgSoftgel, Liquidmid

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Oil-based; softgel or liquid only. Viscous and dark red; usually filled in 500 mg or 1,000 mg softgels. Fishy odor is milder than fish oil but present.

Formulation notes

Shellfish allergen; must be declared on the label. Count its EPA+DHA toward the total omega-3 in a formula that also uses fish or algal oil. Mild antiplatelet effect at higher doses.

  • Allergen: shellfish
  • Notable drug interactions

Sources

  1. Lipid-modifying effects of krill oil in humans: systematic review and meta-analysis of randomized controlled trials. (Ursoniu 2017)PubMed
  2. Clinical effectiveness of krill oil supplementation on cardiovascular health in humans: An updated systematic review and meta-analysis of randomized controlled trials. (Huang 2023)PubMed
  3. Omega-3 Fatty Acids — Health Professional Fact SheetNIH ODS

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