Magnesium Malate

MineralModerate dose evidence

Also known as: magnesium dimalate, Mg malate, magnesium hydrogen malate

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Magnesium paired with malic acid, an intermediate of the Krebs cycle. It is marketed for daytime use in energy and muscle-comfort formulas, based partly on older reports combining magnesium and malate, and is well tolerated with less laxative effect than citrate. The dimalate salt carries about 15.5% elemental magnesium. Direct comparative absorption data in humans are sparse, so its ranges are borrowed from general magnesium research.

Research summary

Supplies magnesium for ATP-dependent enzymes; malate is a mitochondrial substrate, although a distinct effect from the malate portion has not been established in humans.

Dosage

Daily amounts, elemental (16% of the compound is the element).

Lowest studiedTypical rangeHighest studiedUpper limit
100 mg100–350 mg350 mg350 mg

NIH ODS — UL of 350 mg applies to supplemental magnesium only, not magnesium from food

Doses are elemental magnesium. Usually taken with meals earlier in the day. Elemental fraction depends on the grade: magnesium dimalate (Mg(C4H5O5)2, MW ≈ 290) is ≈ 8.4% Mg, while the 1:1 magnesium malate salt (MgC4H4O5, MW ≈ 156) is ≈ 15.5% Mg; 0.155 assumes the 1:1 salt — verify against the supplier's certificate of analysis. Capped at the 350 mg supplemental UL.

Source material: synthetic (magnesium oxide or hydroxide reacted with malic acid)

As supplied: 1:1 salt ≈ 15.5% Mg; dimalate ≈ 8–11% Mg

Forms of Magnesium

FormTypical doseElement %FormatsPrice
Magnesium Malate100–350 mg16%Capsule, Powder, Tabletlow
Magnesium Glycinate200–350 mg14%Capsule, Powder, Tabletlow
Magnesium Citrate150–350 mg16%Capsule, Powder, Tablet, Gummy, Liquidlow
Magnesium Oxide200–350 mg60%Capsule, Powder, Tablet, Gummylow
Magnesium L-Threonate100–144 mg7%Capsule, Powder, Tablethigh
Magnesium Chloride100–300 mg12%Capsule, Powder, Tablet, Liquidlow
Magnesium Taurate100–300 mg9%Capsule, Powder, Tabletmid

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Bulky: 200 mg elemental ≈ 1,300 mg of compound. Tart, pleasant flavor in powders. Tablets are the compact option.

Formulation notes

Separate from bisphosphonates and some antibiotics. Commonly combined with B vitamins in energy formulas.

  • Has an upper limit

Sources

  1. Magnesium — Health Professional Fact SheetNIH ODS
  2. Bioavailability of US commercial magnesium preparations (Firoz 2001)PubMed

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