Streptococcus thermophilus

Probioticlactic acid bacteriaModerate dose evidence

Also known as: S. thermophilus, Streptococcus salivarius subsp. thermophilus, St-21, TH-4, yogurt culture

Add to a formula

Streptococcus thermophilus is one of the two mandatory yogurt starter cultures and a source of the enzyme lactase (beta-galactosidase). It is generally included in blends to support lactose digestion and to complement Lactobacillus and Bifidobacterium strains rather than as a stand-alone probiotic. Human data are modest and mostly from fermented dairy; a small randomized study examined live cultures and lactose digestion in adult lactose malabsorbers. It is inexpensive, robust to freeze-drying, and stable in capsule and powder products.

Research summary

Delivers bacterial lactase to the small intestine and produces lactic acid; studied for support of lactose digestion.

Dosage

Daily amounts, of compound. CFU shown in billions.

Lowest studiedTypical rangeHighest studiedUpper limit
1 B CFU1–5 B CFU

Amounts are in billions of CFU (enter 2 for 2 billion). Raw-material weight assumes a 100 billion CFU/g concentrate (10 mg per billion CFU); manufacturers add a 20–50% CFU overage at fill so the label claim holds through shelf life, and the label should state whether CFU are guaranteed at manufacture or at expiry. Dose range reflects typical blend inclusion levels rather than stand-alone trials.

Standardization: Strain-designated freeze-dried culture; CFU per gram on CoA

Source material: freeze-dried culture

As supplied: Assumes 100 billion CFU/g concentrate (10 mg per billion CFU); adjust to supplier CoA.

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Heat- and moisture-sensitive vegetative cells; capsule or dry powder only.

Formulation notes

Usually cultured on dairy-based media; confirm dairy-free status with the supplier if the finished product is labeled dairy-free. Separate from antibiotic dosing by at least two hours.

Sources

  1. NIH ODS — Probiotics Fact Sheet for Health ProfessionalsNIH ODS
  2. [Influence of live flora on lactose digestion in male adult lactose-malabsorbers after dairy products intake]. (He 2004)PubMed

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