Boswellia Serrata Extract (30% AKBA)
Also known as: 5-Loxin, AprèsFlex, AKBA, 3-O-acetyl-11-keto-beta-boswellic acid, Boswellia AKBA extract
A boswellia gum resin extract enriched to 30% AKBA, the boswellic acid considered most active against 5-lipoxygenase. Because it is more concentrated than 65% extracts, it is used at far lower doses. A 90-day randomized trial of the 5-Loxin extract at 100 and 250 mg per day reported improvements in knee pain and function scores, with the higher dose showing effects within a week. Branded versions include 5-Loxin and AprèsFlex.
Research summary
AKBA inhibits 5-lipoxygenase and matrix metalloproteinase-3, reducing leukotriene production and cartilage-degrading enzyme activity.
Dosage
Daily amounts, of extract.
| Lowest studied | Typical range | Highest studied | Upper limit |
|---|---|---|---|
| 100 mg | 100–250 mg | 250 mg | — |
100 to 250 mg once daily with a meal. In the 90-day trial the 250 mg group reported benefit as early as day 7, while 100 mg took longer. Low dose makes it easy to fit into multi-ingredient joint capsules.
Standardization: 30% AKBA
Source material: gum resin extract
Forms of Boswellia
| Form | Typical dose | Element % | Formats | Price |
|---|---|---|---|---|
| Boswellia Serrata Extract (30% AKBA) | 100–250 mg | — | Capsule, Tablet, Softgel, Powder | high |
| Boswellia Serrata Extract (65% Boswellic Acids) | 300–500 mg | — | Capsule, Tablet, Softgel, Powder | mid |
Format suitability
- Capsule
- Powder
- Tablet
- Softgel
- Gummy
- Liquid
Bitter resin; small dose makes it manageable in most formats.
Formulation notes
Often stacked with curcumin, collagen, or hyaluronic acid. Absorption improves with dietary fat.
Sources
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