Ginger Root Extract

BotanicaldigestiveStrong dose evidence

Also known as: Zingiber officinale, ginger extract 5% gingerols, ginger rhizome extract, gingerols

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A concentrated extract of ginger rhizome standardized to gingerols, the pungent compounds responsible for most of its studied effects. Meta-analyses of randomized trials support its use for nausea, including pregnancy-related nausea at doses below 1,500 mg per day, and for joint comfort in osteoarthritis. It is a versatile ingredient that appears in digestive, joint, and motion-comfort products, and its warming flavor is easy to build around in powders and gummies.

Research summary

Gingerols and shogaols act on serotonin 5-HT3 receptors in the gut and modulate prostaglandin and leukotriene synthesis, which is associated with reduced nausea and inflammatory signaling.

Dosage

Daily amounts, of extract.

Lowest studiedTypical rangeHighest studiedUpper limit
250–1,000 mg1,500 mg

250 to 1,000 mg per day of a 5% gingerol extract, split into two to four doses for nausea or taken with meals for joint use. Meta-analysis subgroups favored daily amounts under 1,500 mg for nausea relief. High single doses can cause heartburn.

Standardization: 5% gingerols

Source material: rhizome extract

Format suitability

  • Capsule
  • Powder
  • Tablet
  • Softgel
  • Gummy
  • Liquid

Pungent and warming; pleasant in gummies and liquids at modest doses.

Formulation notes

Commonly paired with turmeric, boswellia, or vitamin B6. Mild antiplatelet activity; note for formulas with fish oil and ginkgo.

Sources

  1. Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials. (Bartels 2015)PubMed
  2. A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. (Viljoen 2014)PubMed
  3. Ginger — ExamineExamine

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