Ingredient directory

MSM is an organic sulfur compound found in small amounts in plants, milk, and the body.

Typical: 1,500–3,000 mg

Hyaluronic acid is a large glycosaminoglycan that holds water in skin, joint fluid, and connective tissue.

Typical: 80–200 mg

An amino sugar that is a building block of cartilage glycosaminoglycans, sold as the sulfate salt stabilized with potassium or sodium chloride.

Typical: 1,500 mg

A sulfated glycosaminoglycan that is a major structural component of cartilage, where it holds water and resists compression.

Typical: 800–1,200 mg

SAMe is the body's principal methyl donor, made from methionine and ATP, and participates in neurotransmitter synthesis, phospholipid methylation, and cartilage proteoglycan production.

Typical: 400–1,600 mg

A branded, undenatured (native) type II collagen from chicken sternum cartilage that works through a different route than hydrolyzed collagen: tiny oral doses are thought to induce immune tolerance to joint collagen via gut-associated lymphoid tissue.

Typical: 40 mg

The hydrochloride salt of glucosamine, which is more concentrated and more stable than the sulfate form and therefore cheaper per milligram of glucosamine.

Typical: 1,500 mg

Eggshell membrane is the thin protein layer between an egg's shell and white.

Typical: 500 mg