Best ingredients for liver
Liver function and detoxification pathways. These ingredients are studied for or commonly used for liver. Doses on each page come from NIH guidance and published research.
N-Acetyl-Cysteine (NAC)
Amino acidAn acetylated form of the amino acid cysteine that is the rate-limiting precursor for glutathione, the body's principal intracellular antioxidant.
Typical: 600–1,800 mg
Milk Thistle Extract (80% Silymarin)
BotanicalA seed extract of milk thistle standardized to silymarin, a flavonolignan complex, and the best-known botanical in liver-support formulas.
Typical: 140–420 mg
SAMe (S-Adenosyl-L-Methionine)
OtherSAMe is the body's principal methyl donor, made from methionine and ATP, and participates in neurotransmitter synthesis, phospholipid methylation, and cartilage proteoglycan production.
Typical: 400–1,600 mg
Chlorella
OtherChlorella is a single-celled freshwater green alga, most commonly Chlorella vulgaris, grown in tanks and dried into a fine green powder.
Typical: 2–5 g
Choline Bitartrate
VitaminCholine bitartrate is the tartaric acid salt of choline and the most economical way to add this essential nutrient to a formula.
Typical: 250–550 mg
Artichoke Leaf Extract
BotanicalAn extract of globe artichoke leaves standardized to cynarin and caffeoylquinic acids, used in digestive, liver, and cholesterol-support formulas.
Typical: 320–640 mg
Sulforaphane (Broccoli Seed Extract with Myrosinase)
BotanicalSulforaphane is the isothiocyanate formed when glucoraphanin from broccoli seeds or sprouts meets the enzyme myrosinase.
Typical: 100–400 mg
Sunflower Lecithin
Fatty acidSunflower lecithin is a mixture of phospholipids, chiefly phosphatidylcholine, phosphatidylinositol, and phosphatidylethanolamine, separated from sunflower oil during degumming.
Typical: 1,200–2,400 mg
Schisandra Berry Extract
BotanicalAn extract of the berries of a woody vine native to northern China and Korea, prized in traditional practice as a five-flavor tonic and used in modern adaptogen, liver, and endurance formulas.
Typical: 500–1,000 mg
Dandelion Root
BotanicalThe root of the common dandelion, used in traditional practice as a bitter digestive and liver tonic and in modern formulas for liver support and water balance.
Typical: 500–2,000 mg
L-Methionine
Amino acidAn essential sulfur-containing amino acid that starts every protein chain and is the precursor to S-adenosylmethionine, the body's main methyl donor, as well as cysteine and glutathione.
Typical: 500–1,000 mg
Molybdenum Glycinate
MineralMolybdenum chelated with glycine, one of the forms NIH ODS lists for supplements along with sodium molybdate and molybdenum chloride, with no comparative bioavailability data among them.
Typical: 45–150 mcg